Protein Interface Analysis project

In this project I implemented python modules to analyse the interface of SARS-CoV-2 spike protein (prot_A) which plays a key role in the receptor recognition to the host receptor angiotensin-converting enzyme 2 (ACE2, prot_B). This preliminary study looks for the binding of prot_A with different proteins to diminish binding with Antibody P5A3C8 (prot_H and prot_L) and maintain or increase binding with ACE2 (prot_B). Studying their interfaces will provide insights that could inform future interface redesign efforts for prot_A.

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